Before You Start: Important Context and Warnings
Start gently; the tincture is very strong (1:5). Begin met 5 drops once daily and increase slowly. Pushing your body too hard can cause stress rather than healing. The key is balance, with the first focus on calming the nervous system and minimizing triggers.
The protocol builds gradually, focusing on sensitivity like exhaustion, muscle weakness, nervous system hypersensitivity, and brain fog; following Buhner/TreatLyme principles: start low and slowly increase.
General Guidelines
Add one supplement or herb at a time.
Increase dosage every 5–7 days in small steps.
Track symptoms: energy, heart rate, sleep, tremors, brain fog.
Drink plenty of water (≥2L/day) and rest regularly.
If overstimulated, halve dose or step back one phase.
Test labs after a few months (TSH, thyroid hormones, B12, ferritin, Vitamin D3).
Top 3 Mistakes Starting Buhner Protocol
1. Rushing Antimicrobials
Many ramp up herbs too fast, causing Herx reactions, nervous system overload, crashes, and worsening brain fog. The main issue is neuroinflammation, not bacteria alone. Start by calming the nervous system (skullcap, magnesium, creatine, stabilize sleep) before increasing antimicrobials.
2. Forcing Energy Too Soon
Lyme impairs mitochondria and energy buffering. Trying to do too much too soon leads to crashes. Build energy first (creatine, Q10, magnesium, eleuthero), then increase activity.
3. Adding Too Much at Once
Adding many things simultaneously causes confusion over what helps and what causes side effects, leading to nervous system overstimulation. Add only one new thing every 4–7 days for steadier progress.
Practical Start Order for Sensitive Patients
Phase 1 (2–3 weeks): Magnesium, Creatine, Skullcap, Low-dose Knotweed; calm nervous system.
Phase 2 (weeks 3–6): Add Cat’s Claw, Bidens, Eleuthero, reduce brain fog, boost energy, fewer crashes.
Phase 3 (if needed): Increase doses, add Cryptolepis or Red Sage for brain fog.
The Key to Lasting Recovery
Healing happens when your body has the energy to repair itself, not by maxing out antimicrobials. Long-term success relies on calming the nervous system, repairing mitochondria, and balancing immunity.

Lyme recovery protocol (Buhner-based)
Goal:
stabilize the nervous system
restore energy
support Lyme recovery without overloading the body
Suitable for:
exhaustion
muscle weakness
brain fog
hypersensitive nervous system
Core herbs (foundation of the protocol)
Start these together:
Japanese knotweed (Polygonum cuspidatum)
Cat’s claw (Uncaria tomentosa)
Bidens pilosa
Chinese skullcap (Scutellaria baicalensis) ⭐
> This already forms a complete Buhner-style protocol.
Foundational supplements
Only what is truly necessary:
Magnesium — 200–300 mg
Creatine monohydrate — 3 g/day
Q10 complex (such as Migra complex)
Vitamin D3 + K2
Selenium
> No additional supplements are needed to start.
Starting schedule
Week 1–2 (initiation phase)
Take everything at a low dose:
Herbs: ~10 drops, twice daily
Supplements: full daily dose
Goal:
allow the body to adapt
observe reactions
Week 3–4 (build-up)
Increase herbs slowly to:
15–20 drops
2–3 times per day
> Only increase if stable.
Week 5–8 (stabilization phase)
Maintain the same dosage
No new interventions
Common results:
less overstimulation
fewer crashes
first signs of mental clarity
After 8 weeks — only if needed
Energy still low?
Add Eleutherococcus senticosus
Brain fog still strong?
Add Salvia miltiorrhiza
Infection still clearly active?
Add Cryptolepis sanguinolenta
Many people do not need this step.
Daily schedule
Morning
Knotweed
Cat’s claw
Bidens
Creatine
Q10
D3/K2
Afternoon
Knotweed
Bidens
Evening
Chinese skullcap
Magnesium
Selenium
Important rules
Increase slowly
Stability = success
Energy comes later
Don’t keep adding new interventions
What to realistically expect
Month 1 → calmer nervous system
Month 2 → fewer setbacks
Month 3+ → brain fog and muscle strength improve
After that → energy gradually increases
Nervous system recovery is the start of energy restoration
A body stuck in fight-or-flight cannot heal properly. So don’t ask: “Does she have more energy?”. Ask instead: “Is the body responding more calmly?”
Quick checklist (you can post this somewhere)
Is the protocol working if you notice:
sleep slightly better
less overstimulation
fewer severe bad days
slightly faster recovery after exertion
If these happen, you’re on the right track — even without an increase in energy yet.


